公开(公告)号：US20250137059A1

公开(公告)日：2025-05-01

申请号：US18722756

申请日：2022-12-20

Applicant: THE ASAN FOUNDATION ,  UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION ,  HUMANSCAPE INC.

Inventor： Beom Hee LEE ,  Min Hoo CHANG ,  Sun Hee HEO ,  Hyo Sang DO ,  Min Ji KANG

IPC: C12Q1/6886 ,  A61K31/4245 ,  A61P35/00 ,  C12Q1/48 ,  G01N33/574 ,  G01N33/68

Abstract: A biomarker composition for predicting susceptibility to a therapeutic agent for neurofibromatosis by using Ras activity; and a pharmaceutical composition for preventing or treating neurofibromatosis, including a Ras activity inhibitor. The biomarker composition can accurately diagnose susceptibility to a therapeutic agent for neurofibromatosis by measuring the expression levels of a GTP-bound and activated Ras (Ras-GTP) protein and an activated p-ERK protein or a gene encoding the same in a biological sample of an individual. The pharmaceutical composition inhibits the activity of Ras proteins, and thus can be effectively used for the prevention or treatment of neurofibromatosis in which the activity of the Ras proteins is increased.

公开(公告)号：US11645406B2

公开(公告)日：2023-05-09

申请号：US17068499

申请日：2020-10-12

Applicant: Humanscape Inc.

Inventor： TaeWoo Lee

IPC: G06F21/00 ,  G06F21/62 ,  G06F21/64 ,  G06F16/27 ,  G06F16/23

CPC classification number: G06F21/6218 ,  G06F16/2365 ,  G06F16/27 ,  G06F21/64

Abstract: This application relates to a system for verifying data access and a method thereof. In one aspect, the system includes a service module for receiving a data access request for an original data from a client, and sending a first verification data to the client. The system also includes a verification module for receiving a first data eigenvalue corresponding to the original data from the service module, and generating a first verification fingerprint corresponding to the first data eigenvalue. The system further includes a data module for generating the first verification data by receiving the first verification fingerprint to embed into the original data, and generating a first integrity value by hashing the first verification data. The system further includes a verification database for storing data access information comprising the first data eigenvalue, the first verification fingerprint and the first integrity value in one record identified as the original data.

公开(公告)号：US20240161907A1

公开(公告)日：2024-05-16

申请号：US18462584

申请日：2023-09-07

Applicant: HUMANSCAPE INC.

Inventor： Jong Young JUNG

IPC: G16H30/40 ,  G06T7/00 ,  G06T11/00

CPC classification number: G16H30/40 ,  G06T7/0012 ,  G06T11/00 ,  G06T2207/10132

Abstract: A system for generating and editing ultrasound images according to the present disclosure may include a memory and a processor. The processor may be configured to: based on a probe contacting a skin of a pregnant woman, transmit a signal to an ultrasound device to request that imaging start; and based on that an image signal acquired from the ultrasound device an amount of pixel change on an imaging screen, determine whether the imaging screen is in a paused state. The processor may be configured to: take a snapshot on the imaging screen at a time when the imaging screen is determined to be in the paused state; and based on movement of the probe, determine whether to stop or resume the imaging. Based on a value of a grey scale on the imaging screen exceeding a specified level, the processor may transmit a signal to the ultrasound device to request that the imaging be terminated, and store, in the memory, images captured from a moment of start of the imaging to a moment of termination of the imaging.

公开(公告)号：US11836274B2

公开(公告)日：2023-12-05

申请号：US17068565

申请日：2020-10-12

Applicant: Humanscape Inc.

Inventor： TaeWoo Lee

IPC: G06F21/64 ,  G06F16/27 ,  G06F21/62 ,  G06F16/24 ,  G06F16/23

CPC classification number: G06F21/64 ,  G06F16/2365 ,  G06F16/24 ,  G06F16/27 ,  G06F21/62

Abstract: A system includes a data module for receiving an original data and a verification fingerprint, and generating a verification data by inserting the verification fingerprint into an embeddable location of the original data. The system also includes an interpretation module for generating data type information of the original data, and deriving an input-enabled location from an embedding location preset list of the original data, wherein the input-enabled location is included in an inactive area of the original data. The system further includes a preset database for storing the embedding location preset list according to the data type information.

公开(公告)号：US20240175872A1

公开(公告)日：2024-05-30

申请号：US18552133

申请日：2022-03-21

Applicant: THE ASAN FOUNDATION ,  UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION ,  HUMANSCAPE INC.

Inventor： Chong Jai KIM ,  Kyung Gon KIM ,  Beom Hee LEE ,  Eun Na KIM ,  Min Hoo CHANG ,  Hwangkyo JEONG ,  Hyo-Sang DO

IPC: G01N33/574 ,  C12Q1/6886 ,  G01N33/50

CPC classification number: G01N33/57407 ,  C12Q1/6886 ,  G01N33/5011 ,  C12Q2600/136 ,  C12Q2600/158 ,  G01N2333/70596 ,  G01N2333/912 ,  G01N2333/96486

Abstract: The present invention relates to a composition for the differential diagnosis of malignant peripheral nerve sheath tumor (MPNST), a differential diagnosis kit comprising same, a method for providing information required for differential diagnosis of MPNST using same, a method for screening materials for preventing, alleviating, and treating MPNST, and the like. Using the composition capable of detecting the protein marker of the present invention has the effect of making it possible to predict and diagnose whether a malignant tumor has occurred in a patient with neurofibromatosis type 1.

公开(公告)号：US20220019697A1

公开(公告)日：2022-01-20

申请号：US17068565

申请日：2020-10-12

Applicant: Humanscape Inc.

Inventor： TaeWoo LEE

IPC: G06F21/64

Abstract: This application relates to a system for embedding digital verification fingerprint and method thereof. In one aspect, the system includes a data module for receiving an original data and a verification fingerprint, and generating a verification data by inserting the verification fingerprint into an embeddable location of the original data. The system also includes an interpretation module for generating data type information of the original data, and deriving an input-enabled location from an embedding location preset list of the original data, wherein the input-enabled location is included in an inactive area of the original data. The system further includes a preset database for storing the embedding location preset list according to the data type information.

公开(公告)号：US20220019683A1

公开(公告)日：2022-01-20

申请号：US17068499

申请日：2020-10-12

Applicant: Humanscape Inc.

Inventor： TaeWoo LEE

IPC: G06F21/62 ,  G06F16/23 ,  G06F16/27 ,  G06F21/64

Abstract: This application relates to a system for verifying data access and a method thereof. In one aspect, the system includes a service module for receiving a data access request for an original data from a client, and sending a first verification data to the client. The system also includes a verification module for receiving a first data eigenvalue corresponding to the original data from the service module, and generating a first verification fingerprint corresponding to the first data eigenvalue. The system further includes a data module for generating the first verification data by receiving the first verification fingerprint to embed into the original data, and generating a first integrity value by hashing the first verification data. The system further includes a verification database for storing data access information comprising the first data eigenvalue, the first verification fingerprint and the first integrity value in one record identified as the original data.