Provided are systems, methods, and computer program products for data-driven optimization of onboard data collection, comprising identifying a condition in a roadway associated with an operation of autonomous vehicles (AVs) that may be further optimized to improve performance of one or more AVs; and generating condition capture instructions to communicate to the AVs, wherein the condition capture instructions comprise one or more parameters of a storage request in one or more roadways predicted to exhibit the condition in the roadway; and when at least one instruction in the one or more condition capture instructions is received by an AV, the at least one instruction is configured to cause the AV to collect condition information in the roadway at a time when the condition is predicted to be present in the roadway.