- 专利标题： COMBINATION THERAPY INCLUDING A KRAS G12C INHIBITOR AND ONE OR MORE ADDITIONAL PHARMACEUTICALLY ACTIVE AGENTS FOR THE TREATMENT OF CANCERS
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申请号： US18545932申请日： 2023-12-19
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公开(公告)号： US20240245686A1公开(公告)日： 2024-07-25
- 发明人: James Russell LIPFORD , Jude Robert CANON , Anne Y. SAIKI , Karen Louise REX
- 申请人： Amgen Inc.
- 申请人地址： US CA Thousand Oaks
- 专利权人： Amgen Inc.
- 当前专利权人： Amgen Inc.
- 当前专利权人地址： US CA Thousand Oaks
- 主分类号： A61K31/519
- IPC分类号： A61K31/519 ; A61K31/555 ; A61P35/00 ; C07K16/28
摘要：
The present invention provides combination therapy that includes an KRASG12C inhibitor, such as
or a pharmaceutically acceptable salt thereof, and one or more additional pharmaceutically active agents, particularly for the treatment of cancers. The invention also relates to pharmaceutical compositions that contain an KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers.
or a pharmaceutically acceptable salt thereof, and one or more additional pharmaceutically active agents, particularly for the treatment of cancers. The invention also relates to pharmaceutical compositions that contain an KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers.
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