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公开(公告)号:US20200222407A1
公开(公告)日:2020-07-16
申请号:US16687563
申请日:2019-11-18
Applicant: Amgen Inc.
Inventor: James Russell LIPFORD , Jude Robert CANON , Anne Y. SAIKI , Karen Louise REX
IPC: A61K31/519 , A61P35/00
Abstract: The present invention provides combination therapy that includes an KRASG12C inhibitor, such as or a pharmaceutically acceptable salt thereof, and one or more additional pharmaceutically active agents, particularly for the treatment of cancers. The invention also relates to pharmaceutical compositions that contain an KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers.
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公开(公告)号:US20240245686A1
公开(公告)日:2024-07-25
申请号:US18545932
申请日:2023-12-19
Applicant: Amgen Inc.
Inventor: James Russell LIPFORD , Jude Robert CANON , Anne Y. SAIKI , Karen Louise REX
IPC: A61K31/519 , A61K31/555 , A61P35/00 , C07K16/28
CPC classification number: A61K31/519 , A61P35/00 , A61K31/555 , C07K16/2818
Abstract: The present invention provides combination therapy that includes an KRASG12C inhibitor, such as
or a pharmaceutically acceptable salt thereof, and one or more additional pharmaceutically active agents, particularly for the treatment of cancers. The invention also relates to pharmaceutical compositions that contain an KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers.-
公开(公告)号:US20230248729A1
公开(公告)日:2023-08-10
申请号:US18137610
申请日:2023-04-21
Applicant: AMGEN INC.
Inventor: Haby HENARY , James Russell LIPFORD , Victor J. CEE
IPC: A61K31/519 , A61P35/00 , A61K31/53 , A61K31/5375
CPC classification number: A61K31/519 , A61P35/00 , A61K31/53 , A61K31/5375
Abstract: Provided herein are methods of administering a KRAS G12C inhibitor to a cancer subject.
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公开(公告)号:US20240139193A1
公开(公告)日:2024-05-02
申请号:US17769251
申请日:2020-10-14
Applicant: AMGEN INC.
Inventor: Haby HENARY , James Russell LIPFORD
IPC: A61K31/519 , A61K31/497 , A61P35/00
CPC classification number: A61K31/519 , A61K31/497 , A61P35/00
Abstract: Provided herein are methods of administering a KRAS G12C inhibitor in combination with a SHP2 inhibitor to a cancer subject.
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公开(公告)号:US20220378787A1
公开(公告)日:2022-12-01
申请号:US17871178
申请日:2022-07-22
Applicant: Amgen Inc.
Inventor: Haby HENARY , James Russell LIPFORD , VIctor J. CEE
IPC: A61K31/505 , A61P35/00
Abstract: Provided herein are methods of administering a KRAS G12C inhibitor to a cancer subject.
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公开(公告)号:US20240408089A1
公开(公告)日:2024-12-12
申请号:US18422704
申请日:2024-01-25
Applicant: Amgen Inc.
Inventor: Haby HENARY , James Russell LIPFORD , Victor J. CEE
IPC: A61K31/505 , A61K9/00 , A61K31/53 , A61K31/5355 , A61K39/00 , A61P35/00
Abstract: Provided herein are methods of administering a KRAS G12C inhibitor to a cancer subject.
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公开(公告)号:US20230121955A1
公开(公告)日:2023-04-20
申请号:US17870573
申请日:2022-07-21
Applicant: Amgen Inc.
Inventor: James Russell LIPFORD , Jude Robert CANON , Anne Y. SAIKI , Karen Louise REX
IPC: A61K31/519 , A61P35/00 , C07K16/28 , A61K31/555
Abstract: The present invention provides combination therapy that includes an KRASG12C inhibitor, such as or a pharmaceutically acceptable salt thereof, and one or more additional pharmaceutically active agents, particularly for the treatment of cancers. The invention also relates to pharmaceutical compositions that contain an KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers.
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公开(公告)号:US20240173328A1
公开(公告)日:2024-05-30
申请号:US18545953
申请日:2023-12-19
Applicant: Amgen Inc.
Inventor: James Russell LIPFORD , Jude Robert CANON , Anne Y. SAIKI , Karen Louise REX
IPC: A61K31/519 , A61P35/00
CPC classification number: A61K31/519 , A61P35/00 , A61K31/555
Abstract: The present invention provides combination therapy that includes an KRASG12C inhibitor, such as
or a pharmaceutically acceptable salt thereof, and one or more additional pharmaceutically active agents, particularly for the treatment of cancers. The invention also relates to pharmaceutical compositions that contain an KRASG12C inhibitor and one or more additional pharmaceutically active agents for the treatment of cancers.-
公开(公告)号:US20240082251A1
公开(公告)日:2024-03-14
申请号:US18503009
申请日:2023-11-06
Applicant: AMGEN INC.
Inventor: Haby HENARY , James Russell LIPFORD , Victor J. CEE
IPC: A61K31/519 , A61K31/53 , A61K31/5375 , A61P35/00
CPC classification number: A61K31/519 , A61K31/53 , A61K31/5375 , A61P35/00
Abstract: Provided herein are methods of administering a KRAS G12C inhibitor to a cancer subject.
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公开(公告)号:US20230028414A1
公开(公告)日:2023-01-26
申请号:US17785852
申请日:2020-12-15
Applicant: AMGEN INC.
Inventor: Haby HENARY , James Russell LIPFORD , Victor J. CEE
IPC: A61K31/519 , A61K31/5375 , A61K31/53 , A61P35/00
Abstract: Provided herein are methods of administering a KRAS G12C inhibitor to a cancer subject.
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