A decorative panel, in particular a floor panel, ceiling panel or wall panel, including a core provided with an upper side and a lower side, a decorative top structure affixed, either directly or indirectly, on said upper side of the core, a first panel edge including a first coupling profile, and a second panel edge including a second coupling profile being designed to engage interlockingly with said first coupling profile of an adjacent panel, both in horizontal and in vertical direction.