- 专利标题: RECOMBINANT YEAST HOST CELL EXPRESSING AN HYDROLASE
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申请号: US18587167申请日: 2024-02-26
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公开(公告)号: US20240254468A1公开(公告)日: 2024-08-01
- 发明人: Trisha Barrett , Aaron Argyros
- 申请人: Lallemand Hungary Liquidity Management LLC
- 申请人地址: HU Budapest
- 专利权人: Lallemand Hungary Liquidity Management LLC
- 当前专利权人: Lallemand Hungary Liquidity Management LLC
- 当前专利权人地址: HU Budapest
- 主分类号: C12N9/24
- IPC分类号: C12N9/24 ; C12N1/18 ; C12N9/10 ; C12N9/48 ; C12P7/10
摘要:
The present disclosure concerns a recombinant yeast host cell exhibiting higher stability and, in some embodiments, higher fermentation performance. The recombinant yeast host cell stability has a limited ability to express an hydrolase during its propagation phase. In return, this limits the cleavage of a yeast cellular component during or after propagation which may be detrimental to the stability and/or fermentation performances. The recombinant yeast host cell expresses a heterologous hydrolase under the control of a heterologous promoter (for limiting the expression of the heterologous hydrolase during propagation and favoring the expression of the heterologous hydrolase during fermentation).
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