- 专利标题： DEOPTIMIZED SARS-COV-2 VARIANTS AND METHODS AND USES THEREOF
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申请号： US18574973申请日： 2022-06-30
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公开(公告)号： US20240299533A1公开(公告)日： 2024-09-12
- 发明人: Steffen Mueller , John Robert Coleman , Ying Wang , Chen Yang , Yutong Song
- 申请人： Codagenix Inc. , Serum Institute of India Private Limited
- 申请人地址： US NY Farmingdale
- 专利权人： Codagenix Inc.,Serum Institute of India Private Limited
- 当前专利权人： Codagenix Inc.,Serum Institute of India Private Limited
- 当前专利权人地址： US NY Farmingdale; IN Hadapsar, Pune
- 国际申请： PCT/US22/35824 2022.06.30
- 进入国家日期： 2023-12-28
- 主分类号： A61K39/215
- IPC分类号： A61K39/215 ; A61K9/00 ; A61K39/00 ; A61P31/14 ; C07K14/005 ; C12N7/00
摘要：
Described herein are modified SARS-CoV-2 variants. These viruses have been recoded, for example, codon deoptimized or codon pair bias deoptimized and are useful for reducing the likelihood or severity of a SARS-CoV-2 variant infection, preventing a SARS-CoV-2 variant infection, eliciting and immune response, or treating a SARS-CoV-2 variant infection.
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