发明公开
- 专利标题: Compositions and Methods for Treating Cancer with Anti-CD123 Immunotherapy
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申请号: US18733957申请日: 2024-06-05
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公开(公告)号: US20240309102A1公开(公告)日: 2024-09-19
- 发明人: Rimas J. Orentas , Dina Schneider , Boro Dropulic , Dimiter S. Dimitrov , Zhong Zhu
- 申请人: Lentigen Technology, Inc. , The U.S.A., as represented by the Secretary, Department of Health and Human Services
- 申请人地址: US MD Gaithersburg
- 专利权人: Lentigen Technology, Inc.,The U.S.A., as represented by the Secretary, Department of Health and Human Services
- 当前专利权人: Lentigen Technology, Inc.,The U.S.A., as represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址: US MD Gaithersburg
- 分案原申请号: US17095982 2020.11.12
- 主分类号: C07K16/28
- IPC分类号: C07K16/28 ; A61K35/17 ; A61K38/00 ; C07K14/705 ; C07K14/725 ; C12N15/10 ; C12N15/86
摘要:
Chimeric antigen receptors containing CD123 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.
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