- 专利标题： INTERLEUKIN-1 ALPHA CHIMERIC PROTEIN
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申请号： US18574857申请日： 2022-07-08
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公开(公告)号： US20240358826A1公开(公告)日： 2024-10-31
- 发明人: Nikolai KLEY , Erik DEPLA , Joris WAUMAN , Enkeleda NAKUCI , Yen-Ching HO , Alexander Lee KLEY
- 申请人： Orionis Biosciences, Inc. , Orionis Biosciences BV
- 申请人地址： US MA Waltham
- 专利权人： Orionis Biosciences, Inc.,Orionis Biosciences BV
- 当前专利权人： Orionis Biosciences, Inc.,Orionis Biosciences BV
- 当前专利权人地址： US MA Waltham
- 国际申请： PCT/US22/73559 2022.07.08
- 进入国家日期： 2023-12-28
- 主分类号： A61K39/39
- IPC分类号： A61K39/39 ; A61K38/00 ; A61K39/00 ; A61K39/145 ; A61K39/215 ; A61K39/395 ; C07K14/545 ; C07K16/30
摘要：
The present invention relates, in part, to chimeric proteins, chimeric protein complexes, vaccine compositions, and adjuvants that include IL-1α or pro-IL-1α and their use as therapeutic agents or vaccines. The present invention further relates to methods of treatment of various diseases, such as infectious diseases and cancer and methods of vaccination.
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