Techniques discussed herein facilitate configuration of network slices for a User Equipment (UE) supporting constraints on simultaneous operation of slices. One example embodiment is a UE device configured to: transmit a registration request message to request registration on a set of requested network slices; and receive a registration accept message indicating the UE is registered to a set of allowed network slices, and wherein the registration accept message indicates slice compatibility information for each allowed network slice of the set of allowed network slices for the UE, wherein the slice compatibility information for each allowed network slice indicates whether or not other configured network slices of the set of configured network slices are compatible with the configured network slice for simultaneous operation by the UE.