Invention Application
- Patent Title: METHOD FOR TREATING AND/OR PREVENTING REGNASE-1-RELATED DISEASE
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Application No.: US18753584Application Date: 2024-06-25
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Publication No.: US20250018014A1Publication Date: 2025-01-16
- Inventor: Shizuo AKIRA , Takashi SATOH , Hiroki TANAKA , Keiko SAITO , Yusuke YAMAGISHI
- Applicant: OSAKA UNIVERSITY , CHUGAI SEIYAKU KABUSHIKI KAISHA
- Applicant Address: JP Osaka; JP Tokyo
- Assignee: OSAKA UNIVERSITY,CHUGAI SEIYAKU KABUSHIKI KAISHA
- Current Assignee: OSAKA UNIVERSITY,CHUGAI SEIYAKU KABUSHIKI KAISHA
- Current Assignee Address: JP Osaka; JP Tokyo
- Priority: JP2018-108400 20180606,JP2018-167326 20180906,JP2018-229845 20181207,JP2019-089270 20190509
- Main IPC: A61K38/45
- IPC: A61K38/45 ; A61K38/00 ; A61K38/17 ; A61K39/00 ; A61P13/12 ; A61P17/02 ; A61P17/06 ; A61P25/00 ; A61P27/02 ; A61P37/06 ; C07K7/64 ; C07K16/40 ; C12Q1/48 ; G01N33/573

Abstract:
The present invention found that, for example, inhibiting phosphorylation of a Ser residue in Regnase-1 is effective in treating and/or preventing diseases. The invention also found that, for example, inhibiting the binding of Regnase-1 with at least one factor selected from the group consisting of TBK1, IKKi, Act-1, IKK, and IRAK is effective in treating and/or preventing diseases.
Information query
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