Invention Application
- Patent Title: COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CORONAVIRAL RELATED DISEASES
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Application No.: US18580986Application Date: 2022-07-20
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Publication No.: US20250092016A1Publication Date: 2025-03-20
- Inventor: Denghui BAO , Fengfeng GUO , Matthew James HESSE , Viktor HORNAK , Sajan JOSEPH , Thomas Martin KIRRANE, JR. , Haiyao LIN , Bo LIU , Yanan MIAO , Heinz Ernst MOSER , Julien PAPILLON , Yang QU , Lei SHI , Jun YUAN , Teng ZHANG
- Applicant: NOVARTIS AG
- Applicant Address: CH Basel
- Assignee: NOVARTIS AG
- Current Assignee: NOVARTIS AG
- Current Assignee Address: CH Basel
- International Application: PCT/IB2022/056712 WO 20220720
- Main IPC: C07D401/14
- IPC: C07D401/14 ; A61K31/4725 ; A61K31/501 ; A61K31/506 ; A61P31/14 ; C07D401/04

Abstract:
Provided herein are compounds and compositions for treating, managing or preventing coronaviral related diseases. In particular, provided herein are compounds which are inhibitors of SARS-CoV-2 main protease (Mpro), pharmaceutical compositions comprising such compounds, method for synthesizing such compounds and methods of using such compounds and compositions for the treatment, management or prevention of coronaviral related diseases.
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