A self-sealing valve for an inflatable object such as a vehicle tire or tube in which the valve is comprised of an aperture through the wall of the casing of the tire or tube and includes a thin flexible and deformable piece of material sealed to the inner wall of the casing or tube and having an aperture therein offset from the aperture in the casing or tube which will be displaced upon entrance of a hollow tube through the apertures in the casing and thin piece of material to allow entrance of air into the casing. The pressure of the inflating air or medium introduced through the hollow tubular member will cause the thin flexible and deformable piece of material to conform to the inner wall of the casing to seal the aperture therethrough.