Invention Grant
- Patent Title: Pyrroline derivatives
- Patent Title (中): 吡咯衍生物
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Application No.: US3632605DApplication Date: 1967-07-13
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Publication No.: US3632605APublication Date: 1972-01-04
- Inventor: DEBARRE FRANCOIS , POIGET GILBERT
- Applicant: RHONE POULENC SA
- Assignee: Rhone Poulenc Sa
- Current Assignee: Rhone Poulenc Sa
- Priority: FR70348 1966-07-21; FR80834 1966-10-20; FR108081 1967-05-26
- Main IPC: C07D207/20
- IPC: C07D207/20 ; C07D207/22 ; C07D207/24 ; C07D207/26 ; C07D207/277 ; C07D27/14
Abstract:
PYRROLINE DERIVATIVES OF THE FORMULA:
WHEREIN R AND R'' ARE THE SAME OR DIFFERENT AND EACH REPRESENTS A HYDROGEN ATOM OR AN ALKYL GROUP CONTAINING 1 TO 5 CARBON ATOMS (PREFERABLY METHYL), AND THE BENZENE RING IS UNSUBSTITUTED OR CARRIES ONE OR MORE SUBSITUENTS SELECTED FORM HALOGEN ATOMS, ALKYL AND ALKOXY GROUPS CONTAINING 1 TO 5 CARBON ATOMS, AND GYDROXY, NITRO AND AMINO GROUPS, AND THEIR ACID ADDITION SALS, POSSESS PHARMACODYNAMIC PROPERTIES. THEY ACT ON THE CENTRAL NERVOUS SYSTEM, AND ARE ESPECIALLY USEFUL AS ANTI-DEPRESSANTS; FURTHERMORE, THEY SHOW A HYPERTENSIVE EFFECT.
2-(R-N(-R'')-),4-PHENYL-1-PYRROLINE
WHEREIN R AND R'' ARE THE SAME OR DIFFERENT AND EACH REPRESENTS A HYDROGEN ATOM OR AN ALKYL GROUP CONTAINING 1 TO 5 CARBON ATOMS (PREFERABLY METHYL), AND THE BENZENE RING IS UNSUBSTITUTED OR CARRIES ONE OR MORE SUBSITUENTS SELECTED FORM HALOGEN ATOMS, ALKYL AND ALKOXY GROUPS CONTAINING 1 TO 5 CARBON ATOMS, AND GYDROXY, NITRO AND AMINO GROUPS, AND THEIR ACID ADDITION SALS, POSSESS PHARMACODYNAMIC PROPERTIES. THEY ACT ON THE CENTRAL NERVOUS SYSTEM, AND ARE ESPECIALLY USEFUL AS ANTI-DEPRESSANTS; FURTHERMORE, THEY SHOW A HYPERTENSIVE EFFECT.
2-(R-N(-R'')-),4-PHENYL-1-PYRROLINE
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