发明授权
- 专利标题: Zero order release constant elution rate drug dosage
- 专利标题(中): 零级释放持续释放速率药物剂量
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申请号: US3641237D申请日: 1970-09-30
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公开(公告)号: US3641237A公开(公告)日: 1972-02-08
- 发明人: GOULD FRANCIS E , SHEPHERED THOMAS H
- 申请人: NAT PATENT DEV CORP
- 专利权人: Nat Patent Dev Corp
- 当前专利权人: Nat Patent Dev Corp
- 优先权: US7673870 1970-09-30
- 主分类号: C08F20/00
- IPC分类号: C08F20/00 ; A61K9/00 ; A61K9/70 ; C08F20/26 ; A61K27/12
摘要:
ZERO ORDER RELEASE OF WATER SOLUBLE PHARMACEUTICALLY ACTIVE ORGANIC COMPOUNDS ALONE OR ABSORBED OR INCAPSULATED IN HYDROPHILIC POLYMERS IS OBTAINED BY PROVIDING A FILM DIFFUSION BARRIER OF AN ALKOXYETHYL ACRYLATE OR METHACRYLATE POLYMER. TO REDUCE IRRITATIN: AN OUTER COATING OF A NON-IRRITATING WATER SWELLABLE FILM CAN BE ALSO INCORPORATED.
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