Hydrogel contact lenses with lubricious coating thereon

    公开(公告)号:US10449739B2

    公开(公告)日:2019-10-22

    申请号:US15704205

    申请日:2017-09-14

    申请人: Novartis AG

    摘要: The invention is generally related to soft contact lenses which comprise a non-silicone hydrogel lens body and a hydrogel coating thereon. The non-silicone hydrogel lens body is composed of a hydrogel material which is free of silicone and comprises at least 50% by mole of repeating units of at least one hydroxyl-containing vinylic monomer. The hydrogel coating comprises a first polymeric material having first reactive functional groups and a hydrogel layer derived from a second polymeric material having second reactive functional groups, and the hydrogel layer is covalently attached onto the anchor layer through linkages each formed between one first reactive functional group and one second reactive functional group. The soft contact lens has a surface lubricity better than the lubricity of the non-silicone hydrogel lens body and has a friction rating of about 2 or lower after 7 cycles of manual rubbing, a water content of from about 10% to about 85% by weight and an elastic modulus of from about 0.2 MPa to about 1.5 MPa when being fully hydrated at room temperature.

    HYDROGEL CONTACT LENSES WITH LUBRICIOUS COATING THEREON

    公开(公告)号:US20180079158A1

    公开(公告)日:2018-03-22

    申请号:US15704205

    申请日:2017-09-14

    申请人: Novartis AG

    IPC分类号: B29D11/00 G02B1/04 C08F20/00

    摘要: The invention is generally related to soft contact lenses which comprise a non-silicone hydrogel lens body and a hydrogel coating thereon. The non-silicone hydrogel lens body is composed of a hydrogel material which is free of silicone and comprises at least 50% by mole of repeating units of at least one hydroxyl-containing vinylic monomer. The hydrogel coating comprises a first polymeric material having first reactive functional groups and a hydrogel layer derived from a second polymeric material having second reactive functional groups, and the hydrogel layer is covalently attached onto the anchor layer through linkages each formed between one first reactive functional group and one second reactive functional group. The soft contact lens has a surface lubricity better than the lubricity of the non-silicone hydrogel lens body and has a friction rating of about 2 or lower after 7 cycles of manual rubbing, a water content of from about 10% to about 85% by weight and an elastic modulus of from about 0.2 MPa to about 1.5 MPa when being fully hydrated at room temperature.

    Polyacrylic acid-type water absorbent resin and method for producing same
    9.
    发明授权
    Polyacrylic acid-type water absorbent resin and method for producing same 有权
    聚丙烯酸型吸水性树脂及其制造方法

    公开(公告)号:US09315640B2

    公开(公告)日:2016-04-19

    申请号:US14723026

    申请日:2015-05-27

    摘要: Provided is a method for producing a water absorbent resin, which promotes the formation of interconnected voids (continuous gas bubbles) in a foamed polymer (foam-like water absorbent resin) by a more convenient method, and produces with high efficiency a water absorbent resin which exhibits a high water absorption rate even when stepped into a sheet form or a powder form in hygiene articles and the like. Disclosed is a method for producing a polyacrylic acid-type water absorbent resin, comprising (A) a step of obtaining an aqueous solution of acrylic acid-type monomers containing gas bubbles dispersed therein; (B) a step of polymerizing the aqueous monomer solution and thereby obtaining a foamed polymer; and (C) a step of heating and drying the foamed polymer, wherein gas bubbles are incorporated such that the volumetric expansion factor defined by the following formula (1); [Formula 1] Volumetric expansion factor=(Volume of aqueous monomer solution after gas bubble dispersion)/(volume of aqueous monomer solution before gas bubble dispersion)  Formula (1); exceeds 1.1 times, and the aqueous monomer solution having a monomer concentration defined by the following formula (2); [Formula 2] Monomer concentration [wt %]=(Weight of a monomer)/{(weight of a monomer)+(weight of solvent)}×100  Formula (2); of 40% by weight or greater is boiling polymerized at a temperature of 100° C. or higher.

    摘要翻译: 提供一种通过更方便的方法促进发泡聚合物(泡沫状吸水性树脂)中形成互连空隙(连续气泡)的吸水性树脂的制造方法,高效率地制造吸水性树脂 即使在卫生用品等中成为片状或粉末状时,也显示出高的吸水率。 公开了一种聚丙烯酸型吸水性树脂的制造方法,其特征在于,包括:(A)获得含有分散在其中的气泡的丙烯酸型单体的水溶液的工序; (B)使单体水溶液聚合,得到发泡聚合物的工序; 和(C)加热和干燥发泡聚合物的步骤,其中加入气泡,使得由下式(1)定义的体积膨胀系数; [式1]体积膨胀系数=(气泡分散后的单体水溶液体积)/(气泡分散前的单体溶液的体积)式(1) 超过1.1倍,单体浓度由下式(2)定义的单体水溶液; [式2]单体浓度[wt%] =(单体重量)/ {(单体重量)+(溶剂重量)}×100式(2) 为40重量%以上时,在100℃以上的温度下进行沸腾聚合。

    Hydrogelling fibers and fibrous structures
    10.
    发明授权
    Hydrogelling fibers and fibrous structures 有权
    水凝纤维和纤维结构

    公开(公告)号:US09259506B2

    公开(公告)日:2016-02-16

    申请号:US13856481

    申请日:2013-04-04

    摘要: Fibers or one-dimensional, two-dimensional, or three-dimensional fibrous structures configured to be hydrogelling, produced from fibers made of a first fiber raw material, whereby the first fiber raw material contains water-soluble polyvinyl alcohol and/or polyvinyl alcohol copolymer, whereby the hydrogelling configuration of the fibers or fibrous structures is achieved by tempering the fiber raw material at a predetermined tempering temperature that is preferably higher than the glass transition temperature and/or lower than the melting or decomposition temperature of the first fiber raw material employed, as well as by tempering for a predetermined tempering duration, and whereby the fiber raw material is cross-linked by the tempering.

    摘要翻译: 由第一纤维原料制成的纤维制成的纤维或一维,二维或三维纤维结构物构成水凝,由此第一纤维原料含有水溶性聚乙烯醇和/或聚乙烯醇共聚物 由此纤维或纤维结构体的水凝状态是通过优选高于玻璃化转变温度的预定回火温度和/或低于所使用的第一纤维原料的熔解或分解温度来回火纤维原料来实现的 ,并且通过回火预定的回火持续时间,并且由此纤维原料通过回火而交联。