WHEREIN A1, A2, A3, A4, A5 and B, taken separately, each represents hydrogen, halogen, halomethyl, alkyl, alkoxy, nitro, cyano or amino, and A5 and B, taken together, represent a bivalent radical selected from the group consisting of alkylene, alkenylene and alkadienylene having 3 to 5 carbon atoms and alkylene dioxy having 1 to 3 carbon atoms, said bivalent radical being connected to two adjacent carbon atoms of the benzene nucleus, WITH THE PROVISO THAT WHEN A1, A2, A3, A4, A5 and B are all hydrogen atoms, the diphenyl-methylene radical is in the ortho or meta position with regard to the nitrogen atom in the piperidine nucleus, AND THE ADDITION SALTS THEREOF WITH PHARMACEUTICALLY ACCEPTABLE INORGANIC OR ORGANIC ACIDS.

Blood circulation activating, anti-arrhythmic and antihistaminic diphenyl-methylene-N-benzyl-piperidines having the general formula