Invention Grant
- Patent Title: Process for the preparation of vincamine
- Patent Title (中): 长春胺的制备方法
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Application No.: US34525573Application Date: 1973-03-27
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Publication No.: US3884927APublication Date: 1975-05-20
- Inventor: MARTEL JACQUES , COSTEROUSSE GERMAIN
- Applicant: ROUSSEL UCLAF
- Assignee: Roussel Uclaf
- Current Assignee: Roussel Uclaf
- Priority: FR7213135 1972-04-14
- Main IPC: C07D461/00
- IPC: C07D461/00 ; C07D57/08
Abstract:
Process for the preparation of vincamine wherein eburnamonine is reacted with an ethynylmagnesium halide to give (20 Alpha ,21 Alpha ) 16 Alpha -ethynyl eburnane 16 Beta -ol, which upon oxidation to vincaminic acid and subsequent methylation provides vincamine. The optically active forms of vincamine can be obtained by using an optically active form of eburnamonine.
Information query
