发明授权
US3926984A 7-{8 2-(2-Thioxo-4-thiazolin-3-yl)-acetamido{9 {0 cephalosporanic acid derivatives
失效
7- {8-(2-硫代-4-噻唑啉-3-基) - 乙酰氨基{9 {O-头孢烷酸衍生物
- 专利标题: 7-{8 2-(2-Thioxo-4-thiazolin-3-yl)-acetamido{9 {0 cephalosporanic acid derivatives
- 专利标题(中): 7- {8-(2-硫代-4-噻唑啉-3-基) - 乙酰氨基{9 {O-头孢烷酸衍生物
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申请号: US51115574申请日: 1974-10-02
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公开(公告)号: US3926984A公开(公告)日: 1975-12-16
- 发明人: TELLER DANIEL M , SELLSTEDT JOHN H , GUINOSSO CHARLES J
- 申请人: AMERICAN HOME PROD
- 专利权人: American Home Prod
- 当前专利权人: American Home Prod
- 优先权: US51115574 1974-10-02
- 主分类号: C07D499/00
- IPC分类号: C07D499/00 ; C07D499/46 ; C07D501/20 ; C07D501/34 ; C07D501/46
摘要:
The invention presents gram-positive and gram-negative antibacterial agents of the structural formula
IN WHICH R1 and R2 are independently -H or alkyl of 1 to 6 carbon atoms, and when taken together, R1 and R2 are trimethylene; R3 is -H, alkyl of 1 to 6 carbon atoms or methylthioethyl; N IS 0 OR 1, WITH THE PROVISO THAT WHEN N IS 1, R3 is -H; and A is a 7-amino-cephalosporin or 6-amino-penicillin moiety.
IN WHICH R1 and R2 are independently -H or alkyl of 1 to 6 carbon atoms, and when taken together, R1 and R2 are trimethylene; R3 is -H, alkyl of 1 to 6 carbon atoms or methylthioethyl; N IS 0 OR 1, WITH THE PROVISO THAT WHEN N IS 1, R3 is -H; and A is a 7-amino-cephalosporin or 6-amino-penicillin moiety.
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