发明授权
US3953494A Reactions involving carbon tetrahalides and .alpha.-methyl ketones or
ketones having .alpha.,.alpha.'-hydrogens
失效
涉及四卤化碳和{60-甲基酮或酮的反应,其具有{60,{60-
- 专利标题: Reactions involving carbon tetrahalides and .alpha.-methyl ketones or ketones having .alpha.,.alpha.'-hydrogens
- 专利标题(中): 涉及四卤化碳和{60-甲基酮或酮的反应,其具有{60,{60-
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申请号: US98078申请日: 1970-12-14
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公开(公告)号: US3953494A公开(公告)日: 1976-04-27
- 发明人: Cal Yale Meyers , Walter Sidney Matthews, III
- 申请人: Cal Yale Meyers , Walter Sidney Matthews, III
- 申请人地址: IL Carbondale
- 专利权人: Southern Illinois University Foundation
- 当前专利权人: Southern Illinois University Foundation
- 当前专利权人地址: IL Carbondale
- 主分类号: C07C45/63
- IPC分类号: C07C45/63 ; C07C51/00 ; C07C51/295 ; C07C51/28 ; C07C67/42
摘要:
A process for preparing aldehydes, ketones, carboxylic acids and esters by reaction of various substrates with carbon tetrahalides in the presence of a strong base. The reactions are accelerated by the presence of a polar solvent. Anions of the substrate attack the carbon tetrahalide to produce a halogenated intermediate and a dihalocarbene. The halogenated intermediate reacts with the base to form the indicated products. By the reactions of this process, primary alcohols are converted to aldehydes, carboxylic acids and esters, secondary alcohols are converted to ketones and ketones having an .alpha.-methyl group or both .alpha. and .alpha.' hydrogens are converted to carboxylic acids and esters. Non .alpha.-methyl ketones having .alpha. but no .alpha.' hydrogens are simply .alpha.-halogenated. The dihalocarbene generated in the reaction may attack the product, solvent, or another substrate to form other products.
公开/授权文献
- USD419839S Corkscrew 公开/授权日:2000-02-01