发明授权
US3957788A 1-Substituted-4-(1,2-diphenylethyl)piperazine derivatives and their
salts and the preparation thereof
失效
1-取代-4-（1,2-二苯基乙基）哌嗪衍生物及其盐及其制备方法
- 专利标题： 1-Substituted-4-(1,2-diphenylethyl)piperazine derivatives and their salts and the preparation thereof
- 专利标题（中）： 1-取代-4-（1,2-二苯基乙基）哌嗪衍生物及其盐及其制备方法
-
申请号： US541351申请日： 1975-01-15
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公开(公告)号： US3957788A公开(公告)日： 1976-05-18
- 发明人: Haruki Nishimura , Hitoshi Uno , Kagayaki Natsuka , Noriaki Shimokawa , Masanao Shimizu , Hideo Nakamura
- 申请人： Haruki Nishimura , Hitoshi Uno , Kagayaki Natsuka , Noriaki Shimokawa , Masanao Shimizu , Hideo Nakamura
- 申请人地址： JA Osaka
- 专利权人： Dainippon Pharmaceutical Co., Ltd.
- 当前专利权人： Dainippon Pharmaceutical Co., Ltd.
- 当前专利权人地址： JA Osaka
- 优先权： JA49-10470 19740123; JA49-28296 19740312; JA49-29683 19740314
- 主分类号： C07D295/02
- IPC分类号： C07D295/02 ; C07D295/03 ; C07D295/096 ; C07D295/145 ; C07D295/08
摘要：
1-Substituted-4-(1,2-diphenylethyl)piperazine derivatives of the formula: ##SPC1##Wherein X is hydroxy, methoxy, methyl or trifluoromethyl; and R is an unsubstituted monocycloalkyl group having 6 to 8 carbon atoms or 2-methoxyphenyl; provided that when X is hydroxy, R is cyclohexyl, and when X is trifluoromethyl, R is 2-methoxyphenyl,And their pharmaceutically acceptable salts, which have excellent analgesic, anti-tussive and anti-inflammatory activities, without undesirable side effect such as narcotic activity, and a process for the preparation thereof.
公开/授权文献
- US5692719A Sheet music stand 公开/授权日：1997-12-02
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