发明授权
US4008719A Osmotic system having laminar arrangement for programming delivery of
active agent
失效
渗透系统具有用于编程递送活性剂的层流布置
- 专利标题: Osmotic system having laminar arrangement for programming delivery of active agent
- 专利标题(中): 渗透系统具有用于编程递送活性剂的层流布置
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申请号: US654195申请日: 1976-02-02
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公开(公告)号: US4008719A公开(公告)日: 1977-02-22
- 发明人: Felix Theeuwes , Atul D. Ayer
- 申请人: Felix Theeuwes , Atul D. Ayer
- 申请人地址: CA Palo Alto
- 专利权人: Alza Corporation
- 当前专利权人: Alza Corporation
- 当前专利权人地址: CA Palo Alto
- 主分类号: A61F9/00
- IPC分类号: A61F9/00 ; A61K9/00 ; A61K9/22 ; A61M31/00
摘要:
An osmotic system for delivering an agent is disclosed. The system comprises a wall surrounding a compartment and has a passageway for delivering agent from the compartment. The wall is formed of a laminae comprising a lamina consisting of a multiplicity of materials in laminar arrangement with a lamina consisting of a material or of a multiplicity of materials to provide a laminated wall that is permeable to agents and maintains its integrity during the delivery of agent. The compartment contains an agent that is soluble in an external fluid and exhibits an osmotic pressure gradient across the wall against the fluid, or the agent has limited solubility in the fluid and is mixed with an osmotically effective compound soluble in the fluid and exhibits an osmotic pressure gradient across the wall against the fluid. In operation, agent is released from the system by fluid being imbibed through the wall into the compartment at a rate controlled by the permeability of the wall and the osmotic pressure gradient across the wall producing a solution containing agent, or a solution of compound containing agent which solution in either operation is released through the passageway at a controlled and continuous rate over a prolonged period of time.
公开/授权文献
- US5749753A Joint connector 公开/授权日:1998-05-12
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