发明授权
- 专利标题: Derivatives of 4-(4-biphenylyl)-butyric acid
- 专利标题(中): 4-(4-联苯基) - 丁酸的衍生物
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申请号: US406196申请日: 1973-10-15
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公开(公告)号: US4021479A公开(公告)日: 1977-05-03
- 发明人: Ernst Seeger , Wolfhard Engel , Josef Nickl , Helmut Teufel
- 申请人: Ernst Seeger , Wolfhard Engel , Josef Nickl , Helmut Teufel
- 申请人地址: DT Ingelheim am Rhein
- 专利权人: Boehringer Ingelheim GmbH
- 当前专利权人: Boehringer Ingelheim GmbH
- 当前专利权人地址: DT Ingelheim am Rhein
- 优先权: DT2112716 19710317; DT2112715 19710317; DT2112840 19710317
- 主分类号: C07C57/58
- IPC分类号: C07C57/58 ; C07C63/333 ; C07C65/14
摘要:
Compounds of the formulas ##STR1## and ##STR2## wherein A is --CH.sub.2 -- or --CH(OH)--,R.sub.1 is hydrogen, halogen or, when R.sub.2 and R.sub.3 are other than both hydrogen, also methyl,R.sub.2 is hydrogen, halogen, cyano, nitro, amino or (alkanoyl of 1 to 4 carbon atoms)-amino,R.sub.3 is hydrogen or halogen,Provided, however, that at least one of R.sub.1, R.sub.2 and R.sub.3 is other than hydrogen, andR.sub.4 is hydrogen or alkyl of 1 to 4 carbon atoms, and non-toxic salts of the free acids (R.sub.4 = H) formed with inorganic or organic bases; the compounds as well as their salts are useful as antiphlogistics and antiproliferatives.
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