发明授权
- 专利标题： Cycloalkenyl analogues of prostaglandins E
- 专利标题（中）： 前列腺素的环烯基类似物E
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申请号： US624099申请日： 1975-10-20
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公开(公告)号： US4066834A公开(公告)日： 1978-01-03
- 发明人: Warren Dexter Woessner , William Gerard Biddlecom , Henry Clifford Arndt , George Peter Peruzzotti , Charles John Sih
- 申请人： Warren Dexter Woessner , William Gerard Biddlecom , Henry Clifford Arndt , George Peter Peruzzotti , Charles John Sih
- 申请人地址： IN Elkhart
- 专利权人： Miles Laboratories, Inc.
- 当前专利权人： Miles Laboratories, Inc.
- 当前专利权人地址： IN Elkhart
- 主分类号： C07C405/00
- IPC分类号： C07C405/00 ; C07C177/00
摘要：
Analogues of prostaglandins A, E, and F in which the C.sub.13 -C.sub.20 chain of the natural prostaglandins is replaced by a cycloalkenyl or a hydroxycycloalkenyl moiety such that vinylene radical and the hydroxyl group of the ring respectively retain their natural sequential positions at C.sub.13 -C.sub.14 and C.sub.15, inhibit aggregation of platelets in vitro and exhibit useful cardiovascular activity in vivo.
公开/授权文献
- US5743997A Sheet material sealing arrangement 公开/授权日：1998-04-28
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