发明授权
- 专利标题: Diacylapomorphines
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申请号: US633650申请日: 1975-11-20
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公开(公告)号: US4080456A公开(公告)日: 1978-03-21
- 发明人: Dieter Seidelmann , Ralph Schmiechen , Reinhard Horowski , Wolfgang Kehr , Dieter Palenschat , Gert Paschelke
- 申请人: Dieter Seidelmann , Ralph Schmiechen , Reinhard Horowski , Wolfgang Kehr , Dieter Palenschat , Gert Paschelke
- 申请人地址: DT Berlin and Bergkamen
- 专利权人: Schering Aktiengesellschaft
- 当前专利权人: Schering Aktiengesellschaft
- 当前专利权人地址: DT Berlin and Bergkamen
- 优先权: DT2154162 19711026
- 主分类号: C07D221/18
- IPC分类号: C07D221/18 ; A61K31/47 ; C07D215/06
摘要:
Diacylapomorphines of the formula ##STR1## wherein R.sub.1 and R.sub.2 are both acyl of 1-17 carbons are symptomatically effective agents in the treatment of motor disorders of the type associated with a dopamine deficiency of the extrapyramidal system of the central nervous system, e.g. Parkinson's disease. Pharmaceutical compositions containing these compounds as an active ingredient are described, as well as new compunds of the above formula wherein R.sub.1 and R.sub.2 are formyl or acyl of 3-17 carbon atoms.
公开/授权文献
- US5214325A Methods and apparatus for ventilating electric machines 公开/授权日:1993-05-25
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