发明授权
- 专利标题: Phenoxyalicyclic carboxylic acid derivatives
- 专利标题(中): 羟基乙酰氧基酸衍生物
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申请号: US365277申请日: 1973-05-30
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公开(公告)号: US4082913A公开(公告)日: 1978-04-04
- 发明人: Yoshio Suzuki , Masayoshi Minai , Noritaka Hamma , Eiichi Murayama , Shunji Aono
- 申请人: Yoshio Suzuki , Masayoshi Minai , Noritaka Hamma , Eiichi Murayama , Shunji Aono
- 申请人地址: JA Osaka
- 专利权人: Sumitomo Chemical Company, Limited
- 当前专利权人: Sumitomo Chemical Company, Limited
- 当前专利权人地址: JA Osaka
- 优先权: JA47-54849 19720601
- 主分类号: C07C62/08
- IPC分类号: C07C62/08 ; A61K20060101 ; A61K31/19 ; A61K31/215 ; A61P9/10 ; A61P29/00 ; C07C20060101 ; C07C51/00 ; C07C61/00 ; C07C61/06 ; C07C61/08 ; C07C61/12 ; C07C62/34 ; C07C63/00 ; C07C67/00 ; C07C69/66 ; C07C69/74 ; C07C69/757 ; C07C69/76
摘要:
Novel anti-atherosclerosis agents having the formula, ##STR1## wherein R is hydrogen or lower alkyl, n and m each signify an integer of 4 - 6, and A is hydrogen or a group of the formula, ##STR2## WHEREIN R and m have the same meanings as defined above. These compounds are produced, for example, by reacting a bisphenolic compound of the formula, ##STR3## with chloroform and a ketone compound of the formula, ##STR4## in the presence of an alkali. Alternatively, they are produced by reacting the bisphenolic compound with .alpha.-halogeno- or .alpha.-hydroxycarboxylic acid derivative of the formula, ##STR5## wherein R and m have the same meanings as defined above, and X is halogen or hydroxyl.
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