发明授权
US4087520A Lowering blood pressure with new
L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptides
失效
用新的L-3-(3,4-二羟基苯基)-2-甲基 - 丙氨酸肽降低血压
- 专利标题: Lowering blood pressure with new L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptides
- 专利标题(中): 用新的L-3-(3,4-二羟基苯基)-2-甲基 - 丙氨酸肽降低血压
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申请号: US665341申请日: 1976-03-09
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公开(公告)号: US4087520A公开(公告)日: 1978-05-02
- 发明人: Franz Braun , Kurt Stach, deceased , by Werner Plattner, executor , Max Thiel , Gisbert Sponer , Karl Dietmann
- 申请人: Franz Braun , Kurt Stach, deceased , by Werner Plattner, executor , Max Thiel , Gisbert Sponer , Karl Dietmann
- 申请人地址: DT Mannheim-Waldhof
- 专利权人: Boehringer Mannheim GmbH
- 当前专利权人: Boehringer Mannheim GmbH
- 当前专利权人地址: DT Mannheim-Waldhof
- 优先权: DT2510634 19750312
- 主分类号: C07K1/113
- IPC分类号: C07K1/113 ; A61K38/00 ; A61K38/05 ; C07C67/00 ; C07C231/00 ; C07C231/02 ; C07K5/06 ; C07K5/065 ; C07K5/083 ; A61K37/00 ; C07C103/52
摘要:
An L-3-(3,4-dihydroxyphenyl)-2-methyl-alanine peptide of the formula ##STR1## wherein A is an alkylene radical which can be substituted by a hydroxyl group or by a phenyl radical which optionally carries at least one hydroxyl group, andR is a hydrogen atom or a lower alkyl radical or a glycyl or alanyl radical,Or a pharmacologically compatible salt thereof. These compounds are outstanding in lowering blood pressure.
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