发明授权
US4092346A Acyl-phenoxy-propanesulfoacids and salts, and artificial sweetening
compositions containing the same
失效
酰基 - 苯氧基 - 丙磺酸和盐,以及含有它们的人造甜味组合物
- 专利标题: Acyl-phenoxy-propanesulfoacids and salts, and artificial sweetening compositions containing the same
- 专利标题(中): 酰基 - 苯氧基 - 丙磺酸和盐,以及含有它们的人造甜味组合物
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申请号: US746350申请日: 1976-12-01
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公开(公告)号: US4092346A公开(公告)日: 1978-05-30
- 发明人: Lorand Farkas , Mihaly Nogradi , Todor Pfliegel , Sandor Antus , Agnes Gottsegen
- 申请人: Lorand Farkas , Mihaly Nogradi , Todor Pfliegel , Sandor Antus , Agnes Gottsegen
- 申请人地址: HU Budapest
- 专利权人: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
- 当前专利权人: Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Rt.
- 当前专利权人地址: HU Budapest
- 优先权: HUOE1448 19740219
- 主分类号: A23L27/30
- IPC分类号: A23L27/30 ; C07C309/11 ; C07C143/24 ; A23L1/236
摘要:
Compounds of the formula (1), or their salts, ##STR1## are prepared as follows: (A) A COMPOUND OF THE FORMULA (II) ##STR2## is reduced; or (B) A COMPOUND OF THE FORMULA (III) ##STR3## is reacted, e.g. after protecting the phenolic hydroxy group attached to position 3 of the ring, with a compound of the formula (IV), ##STR4## or (C) GROUP R.sup.1 of a compound of the formula (V) ##STR5## is removed in an acidic medium, AND, IF DESIRED, THE COMPOUND OF THE FORMULA (I) is converted into salt, or a salt of a compound of the formula (I) is converted into the free acid or another salt thereof.The compounds of the formula (I) and their salts are valuable artificial sweetening agents.In the above formulae"alkyl" is a C.sub.1-4 alkyl group,R is hydrogen or a protecting group capable of splitting off upon hydrogenolysis, preferably benzyl or benzyloxycarbonyl,M+ is a proton or another cation,X is a group of the general formula O.sup.- M.sup.+,Y is halogen, orX and Y together represent an oxygen atom, andR.sup.1 is a protecting group capable of splitting off in acidic media, such as 2-tetrahydropyranyl or 1-ethoxyethyl.
公开/授权文献
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