发明授权
US4094883A 5-Iodo-6-oxo-3-(2'-arylmethoxy-1'-hydroxyethyl)-4-hydroxy-hexanoic acid,
.gamma.-lactone dialkyl acetals
失效
（2- {40-芳基甲氧基-1 {40-羟乙基）-4-羟基 - 己酸，{65-内酯二烷基缩醛
- 专利标题： 5-Iodo-6-oxo-3-(2'-arylmethoxy-1'-hydroxyethyl)-4-hydroxy-hexanoic acid, .gamma.-lactone dialkyl acetals
- 专利标题（中）： （2- {40-芳基甲氧基-1 {40-羟乙基）-4-羟基 - 己酸，{65-内酯二烷基缩醛
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申请号： US784177申请日： 1977-04-04
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公开(公告)号： US4094883A公开(公告)日： 1978-06-13
- 发明人: Robert C. Kelly
- 申请人： Robert C. Kelly
- 申请人地址： MI Kalamazoo
- 专利权人： The Upjohn Company
- 当前专利权人： The Upjohn Company
- 当前专利权人地址： MI Kalamazoo
- 主分类号： C07D309/22
- IPC分类号： C07D309/22 ; C07D493/02 ; C07D493/04 ; C07D307/32
摘要：
The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 (11a-homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxy derivatives thereof. In particular, there are disclosed various bicyclic tetrahydrofuran-containing lactones useful in the above processes, and corresponding acyclic lactones.
公开/授权文献
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