发明授权
US4100177A 4,5-Didehydro-6-hydrox
y-2-arylmethoxymethyl-4.alpha.-tetrahydropyranacetic acid alkyl esters
失效
4,5-二脱氢-6-羟基-2-芳基甲氧基甲基-4 {60-四氢吡喃乙酸烷基酯
- 专利标题： 4,5-Didehydro-6-hydrox y-2-arylmethoxymethyl-4.alpha.-tetrahydropyranacetic acid alkyl esters
- 专利标题（中）： 4,5-二脱氢-6-羟基-2-芳基甲氧基甲基-4 {60-四氢吡喃乙酸烷基酯
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申请号： US784175申请日： 1977-04-04
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公开(公告)号： US4100177A公开(公告)日： 1978-07-11
- 发明人: Robert C. Kelly
- 申请人： Robert C. Kelly
- 申请人地址： MI Kalamazoo
- 专利权人： The Upjohn Company
- 当前专利权人： The Upjohn Company
- 当前专利权人地址： MI Kalamazoo
- 主分类号： C07D309/22
- IPC分类号： C07D309/22 ; C07D493/02 ; C07D493/04
摘要：
The present specification provides novel intermediates and novel processes for the synthesis of Thromboxane B.sub.2 11a-homo-11a-oxa-PGF.sub.2.alpha.), its 15-epimer, and various carboxyl derivatives thereof. In particular, there are disclosed various bicyclic tetrahydrofuran-containing lactones useful in the above processes, and corresponding acyclic lactones.
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