发明授权
US4123533A Fused pyrimidine derivatives and compositions for treating
atherosclerosis containing them
失效
融合的嘧啶衍生物和用于治疗含有它们的动脉粥样硬化的组合物
- 专利标题： Fused pyrimidine derivatives and compositions for treating atherosclerosis containing them
- 专利标题（中）： 融合的嘧啶衍生物和用于治疗含有它们的动脉粥样硬化的组合物
-
申请号： US765595申请日： 1977-02-04
-
公开(公告)号： US4123533A公开(公告)日： 1978-10-31
- 发明人: Istvan Hermecz , Zoltan Meszaros , Sandor Virag , Lelle Vasvari nee Debreczy , Agnes Horvath , Jozsef Knoll , Gyula Sebestyen , Agoston David
- 申请人： Istvan Hermecz , Zoltan Meszaros , Sandor Virag , Lelle Vasvari nee Debreczy , Agnes Horvath , Jozsef Knoll , Gyula Sebestyen , Agoston David
- 申请人地址： HUX Budapest
- 专利权人： Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
- 当前专利权人： Chinoin Gyogyszer es Vegyeszeti Termekek Gyara R.T.
- 当前专利权人地址： HUX Budapest
- 优先权： HUXCI1642 19760212
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/505 ; A61K31/519 ; A61P3/06 ; A61P9/10 ; A61P25/28 ; C07D471/04
摘要：
Compounds of the formula: ##STR1## or pharmaceutically acceptable salts thereof are disclosed wherein R is hydrogen or C.sub.1 to C.sub.6 alkyl;R.sup.2 and R.sup.3 are each hydrogen or together form a valency bond;R.sup.6 is carboxy or C.sub.1 to C.sub.6 alkoxycarbonyl;R.sup.7 and R.sup.8 are each hydrogen or together form a valency bond;R.sup.10 is carboxy or C.sub.1 to C.sub.6 alkoxycarbonyl and the dotted line represents two hydrogen atoms or a valency bond. The compounds are useful in the treatment of atherosclerosis.
公开/授权文献
- US5990673A Digital phase comparator 公开/授权日：1999-11-23