发明授权
- 专利标题: Substituted pyrazines as inhibitors of platelet aggregation
- 专利标题(中): 取代的吡嗪作为血小板聚集的抑制剂
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申请号: US799167申请日: 1977-05-23
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公开(公告)号: US4123613A公开(公告)日: 1978-10-31
- 发明人: Luigi Bernardi , Carlo Elli , Giovanni B. Falconi , Rosella Ferrari
- 申请人: Luigi Bernardi , Carlo Elli , Giovanni B. Falconi , Rosella Ferrari
- 申请人地址: ITX Milan
- 专利权人: Societa Farmaceutici Italia S.p.A.
- 当前专利权人: Societa Farmaceutici Italia S.p.A.
- 当前专利权人地址: ITX Milan
- 优先权: GBX21801/76 19760526
- 主分类号: A61K31/48
- IPC分类号: A61K31/48 ; A61P7/02 ; C07D457/02 ; C07D241/18
摘要:
Novel substituted pyrazine derivatives are disclosed having the general formula (I): ##STR1## where R.sub.1 and R.sub.2 may be methyl, methoxy, halogen (particularly chlorine, bromine or fluorine), or hydrogen, with the proviso that R.sub.1 and R.sub.2 cannot both be hydrogen, and X may be S or NH.These novel substituted pyrazine derivatives show a remarkable activity as inhibitors of platelet aggregation at very low dosages.
公开/授权文献
- US5886772A Film processing apparatus 公开/授权日:1999-03-23
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