发明授权
- 专利标题: Acylation of 7-aminocephalosporanic acids
- 专利标题(中): 7-氨基头孢烷酸的酰化
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申请号: US428037申请日: 1973-12-26
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公开(公告)号: US4179557A公开(公告)日: 1979-12-18
- 发明人: Toshiyasu Ishimaru , Yasutsugu Shimonishi , Hisayuki Sakurai , Minoru Hatanaka
- 申请人: Toshiyasu Ishimaru , Yasutsugu Shimonishi , Hisayuki Sakurai , Minoru Hatanaka
- 申请人地址: JPX
- 专利权人: President of Osaka University
- 当前专利权人: President of Osaka University
- 当前专利权人地址: JPX
- 主分类号: C07D295/185
- IPC分类号: C07D295/185 ; C07D499/00 ; C07D501/06 ; C07D501/04
摘要:
6-Aminoacylamidopenicillanic acid or 7-aminoacylamidocephalosporanic acids are produced in high yields by acylating 6-aminopenicillanic acid or 7-aminocephalosporanic acid with an amino acid, or a functional equivalent thereof, having its amino group protected with N,N-disubstituted .beta.-keto acid amide, and then removing the protecting group from the resulting protected 6-aminoacylamidopenicillanic acid or protected 7-aminoacylamidocephalosporanic acid by hydrolysis.
公开/授权文献
- US6122900A Manufacture of pocketed compound nested coil springs 公开/授权日:2000-09-26
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