发明授权
- 专利标题: System for delivering agent to environment of use over prolonged time
- 专利标题(中): 长时间运送代理使用环境的系统
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申请号: US750701申请日: 1976-12-15
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公开(公告)号: US4180064A公开(公告)日: 1979-12-25
- 发明人: Jorge Heller , Richard W. Baker
- 申请人: Jorge Heller , Richard W. Baker
- 申请人地址: CA Palo Alto
- 专利权人: Alza Corporation
- 当前专利权人: Alza Corporation
- 当前专利权人地址: CA Palo Alto
- 主分类号: A61K9/00
- IPC分类号: A61K9/00 ; A61K9/20 ; A61K31/00 ; A61F5/46 ; A61K9/02 ; A61K31/56 ; A61K47/00 ; A61M31/00
摘要:
A device for the controlled continuous administration of an active agent to an environment of use is disclosed. The device comprises a body of erodible agent release rate controlling material containing an agent dispersed therethrough; the rate controlling material is a hydrophobic poly(carboxylic acid) having one ionizable carboxylic hydrogen for each 8 to 12 carbon atoms, which material erodes at a controlled and continuous rate over a prolonged period of time in response to the environment by a process of carboxylic hydrogen ionization, thereby releasing the dispersed agent at a controlled rate over a prolonged period of time.
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