发明授权
US4200575A 7[(2-Thiazolyl)-2-(oxoimino)acetamido]cephalosporin derivatives
失效
7 [(2-噻唑基)-2-(氧代亚氨基)乙酰氨基]头孢菌素衍生物
- 专利标题: 7[(2-Thiazolyl)-2-(oxoimino)acetamido]cephalosporin derivatives
- 专利标题(中): 7 [(2-噻唑基)-2-(氧代亚氨基)乙酰氨基]头孢菌素衍生物
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申请号: US930041申请日: 1978-08-01
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公开(公告)号: US4200575A公开(公告)日: 1980-04-29
- 发明人: Mitsuo Numata , Tatsuo Nishimura
- 申请人: Mitsuo Numata , Tatsuo Nishimura
- 申请人地址: JPX Osaka
- 专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人: Takeda Chemical Industries, Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX52-94469 19770806
- 主分类号: A61K31/545
- IPC分类号: A61K31/545 ; A61K31/546 ; A61P31/04 ; C07D501/20 ; C07D501/22 ; C07D501/24 ; C07D501/34 ; C07D501/36 ; C07D501/46
摘要:
Novel [2-(syn)-carbamoyloximinoacetamido]cephalosporins of the formula: ##STR1## [wherein, Y.sup.1 is hydrogen, hydroxyl, carbamoyloxy, acyloxy, quaternary ammonium or nitrogen-containing heterocyclic thio; R.sup.1 is alkyl, aralkyl or aryl; R.sup.2 is hydrogen or an ester residue; k is 0 or 1] and a salt thereof show strong antibacterial activities particularly against Gram-negative bacteria and they are useful as antibacterial agents.
公开/授权文献
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