发明授权
US4235771A Water soluble agents effective as immunological adjuvants for
stimulating in the host the immune response to various antigens and
compositions, notably vaccines containing said water soluble agents
失效
作为用于在宿主中刺激各种抗原和组合物的免疫应答的免疫佐剂的水溶性物质,特别是含有所述水溶性试剂的疫苗
- 专利标题: Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens and compositions, notably vaccines containing said water soluble agents
- 专利标题(中): 作为用于在宿主中刺激各种抗原和组合物的免疫应答的免疫佐剂的水溶性物质,特别是含有所述水溶性试剂的疫苗
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申请号: US906002申请日: 1978-05-15
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公开(公告)号: US4235771A公开(公告)日: 1980-11-25
- 发明人: Arlette Adam , Francoise Audibert , Louis Chedid , Jean Choay , Rita Ciorbaru , Fabrielle Ellouz , Dominique Juy , Pierre Lefrancier , Claude Merser , Jean-Francois Petit , Pierre Sinay , Edgar Lederer
- 申请人: Arlette Adam , Francoise Audibert , Louis Chedid , Jean Choay , Rita Ciorbaru , Fabrielle Ellouz , Dominique Juy , Pierre Lefrancier , Claude Merser , Jean-Francois Petit , Pierre Sinay , Edgar Lederer
- 申请人地址: FRX
- 专利权人: Agence Nationale de Valorisation de la Recherche (ANVAR)
- 当前专利权人: Agence Nationale de Valorisation de la Recherche (ANVAR)
- 当前专利权人地址: FRX
- 优先权: FRX7337806 19731023; FRX7422909 19740701
- 主分类号: A61K35/74
- IPC分类号: A61K35/74 ; A61K38/00 ; A61K39/00 ; A61K39/39 ; C07K9/00 ; C07C103/52
摘要:
Water soluble agents effective as immunological adjuvants for stimulating in the host the immune response to various antigens, comprising an acyl-muramic acid group, wherein acyl means acetyl or glycolyl, and a short peptide chain linked to said acyl-muramic acid group, the first and second amino acids of said peptide chain being preferentially alanine and glutamic acid respectively.
公开/授权文献
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