发明授权
US4235916A 2-Methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene and
salts thereof, neuroleptic compositions and method of use
失效
2-甲硫基-6-氟-9-（1-甲基-4-哌啶基） - 噻吨酮及其盐，神经安定剂组合物和使用方法
- 专利标题： 2-Methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene and salts thereof, neuroleptic compositions and method of use
- 专利标题（中）： 2-甲硫基-6-氟-9-（1-甲基-4-哌啶基） - 噻吨酮及其盐，神经安定剂组合物和使用方法
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申请号： US971509申请日： 1978-12-20
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公开(公告)号： US4235916A公开(公告)日： 1980-11-25
- 发明人: Klaus P. Bogeso
- 申请人： Klaus P. Bogeso
- 申请人地址： DKX Copenhagen-Valby
- 专利权人： Kefalas A/S
- 当前专利权人： Kefalas A/S
- 当前专利权人地址： DKX Copenhagen-Valby
- 优先权： GBX54175/77 19771229
- 主分类号： A61K31/4433
- IPC分类号： A61K31/4433 ; A61K31/445 ; A61P25/00 ; C07D409/04 ; A61K31/38 ; C07D417/04
摘要：
The present invention relates to the novel compound 2-methylthio-6-fluoro-9-(1-methyl-4-piperidylidene)-thioxanthene of the formula ##STR1## and its non-toxic acid addition salts, which compounds have strong and longlasting neuroleptic properties and, at the same time, a low degree of undesired side effects such as extrapyrimidal side effects.The invention moreover relates to a method for the preparation of said novel compounds, pharmaceutical compositions containing same, which may be administered to animals, including human beings, orally or parentally.Further the invention relates to a method for producing an antipsychotic effect in warmblooded animals by administering to said animals an antipsychotically effective amount of one of said novel compounds.
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