发明授权
US4242278A Process for the preparation of
2-(2',2',2'-trihalogenoethyl)-4-halogenocyclobutan-1-ones
失效
制备2-(2',2',2'-三卤代乙基)-4-卤代环丁烷-1-酮的方法
- 专利标题: Process for the preparation of 2-(2',2',2'-trihalogenoethyl)-4-halogenocyclobutan-1-ones
- 专利标题(中): 制备2-(2',2',2'-三卤代乙基)-4-卤代环丁烷-1-酮的方法
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申请号: US948126申请日: 1978-10-03
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公开(公告)号: US4242278A公开(公告)日: 1980-12-30
- 发明人: Pierre Martin , Hans Greuter , Eginhard Steiner , Daniel Bellus
- 申请人: Pierre Martin , Hans Greuter , Eginhard Steiner , Daniel Bellus
- 申请人地址: NY Ardsley
- 专利权人: Ciba-Geigy Corporation
- 当前专利权人: Ciba-Geigy Corporation
- 当前专利权人地址: NY Ardsley
- 优先权: CHX4071/77 19770331; CHX14404/77 19771124; CHX1974/78 19780223; CHX9992/78 19780925
- 主分类号: C07C51/60
- IPC分类号: C07C51/60 ; C07C51/62 ; C07C53/50 ; C07C61/15 ; C07C61/40 ; C07C45/45 ; C07C49/105 ; C07C49/115
摘要:
A process for the preparation of 2-(2',2',2',-trihalogenoethyl)-4-halogenocyclobutan-1-ones of the formula ##STR1## in which one of the radicals R.sub.1 and R.sub.2 is methyl and the other is hydrogen or methyl, or R.sub.1 and R.sub.2 together are an alkylene group having 2 to 4 carbon atoms, and X and Y are each chlorine or bromine, comprising reacting a 2,4,4,4-tetrahalogenobutyric acid chloride in the presence of an organic base with an ethylene compound which is disubstituted in 1-position by the radicals R.sub.1 and R.sub.2, as defined above, to form a 2-(2',2',2'-trihalogenoethyl)-2-halogenocyclobutan-1-one and then rearranging the latter, in the presence of a catalyst, into a 2-(2',2',2'-trihalogenoethyl)-4-halogenocyclobutan-1-one of the above formula; said 2-(2',2',2'-trihalogenoethyl)-4-halogenocyclobutan-1-ones being valuable intermediates for the preparation of 2-(2',2'-dihalogenovinyl)-cyclopropanecarboxylic acid and its insecticidally active esters; as well as the 2-(2',2',2'-trihalogenoethyl)-4-halogenocyclobutan-1-ones of the above formula and the intermediates utilized for their preparation.
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