发明授权
US4258057A Prostaglandin derivatives of the .DELTA.2,4-11-deoxy-PEG series
失效
DELTA 2,4-11-脱氧-PEG系列前列腺素衍生物
- 专利标题： Prostaglandin derivatives of the .DELTA.2,4-11-deoxy-PEG series
- 专利标题（中）： DELTA 2,4-11-脱氧-PEG系列前列腺素衍生物
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申请号： US054874申请日： 1979-07-05
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公开(公告)号： US4258057A公开(公告)日： 1981-03-24
- 发明人: Wilhelm Bartmann , Gerhard Beck , Ulrich Lerch , Martin Bickel
- 申请人： Wilhelm Bartmann , Gerhard Beck , Ulrich Lerch , Martin Bickel
- 申请人地址： DEX Frankfurt am Main
- 专利权人： Hoechst Aktiengesellschaft
- 当前专利权人： Hoechst Aktiengesellschaft
- 当前专利权人地址： DEX Frankfurt am Main
- 优先权： DEX2830079 19780708
- 主分类号： C07D317/72
- IPC分类号： C07D317/72 ; A61K31/557 ; A61K31/5575 ; A61P43/00 ; C07C67/00 ; C07C401/00 ; C07C405/00 ; C07F9/535 ; C07F9/54 ; A01N37/00 ; C07C69/74
摘要：
The present invention relates to novel prostaglandin derivatives of the formula I ##STR1## which are structurally related to the naturally occurring prostaglandins and in which R.sup.1 denotes (a) hydrogen or a straight-chain or branched, saturated or unsaturated aliphatic or cycloaliphatic hydrocarbon radical having up to ten carbon atoms or (b) a physiologically acceptable metal or NH.sub.4 ion or an ammonium ion which is derived from a primary, secondary or tertiary amine and R.sup.2 denotes a straight-chain, aliphatic hydrocarbon radical having up to six carbon atoms and to a process for their manufacture.The compounds of the invention are distinguished in particular by gastric acid secretion-inhibiting and ulcer-protective properties.
公开/授权文献
- US4851262A Method of making carbide, nitride and boride powders 公开/授权日：1989-07-25
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