发明授权
- 专利标题: Novel hyaluronidase BMP-8231 and production thereof
- 专利标题(中): 新型透明质酸酶BMP-8231及其制备方法
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申请号: US35719申请日: 1979-05-03
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公开(公告)号: US4258134A公开(公告)日: 1981-03-24
- 发明人: Keizo Yoshida , Takashi Fujii , Hiroyuki Kikuchi
- 申请人: Keizo Yoshida , Takashi Fujii , Hiroyuki Kikuchi
- 申请人地址: JPX Osaka
- 专利权人: Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人: Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人地址: JPX Osaka
- 优先权: JPX53/56313 19780511
- 主分类号: C12N9/26
- IPC分类号: C12N9/26 ; C12R1/465
摘要:
Hyaluronidase obtained from Streptomyces koganeiensis has the following characteristics:(a) Acts as an endo B-hexosaminidase(b) Degrades hyaluronic acid but not chondroitin sulfate A, C, or chondroitin(c) Optimum pH around 4.0(d) Stable pH range 4.0-11.3(e) Optimum temperature around 60.degree. C.(f) Stable a temperature below 60.degree. C.(g) Stable against proteolytic enzymes
公开/授权文献
- US5292967A Process for producing 2,3-difluoro-6-nitrophenol 公开/授权日:1994-03-08
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