发明授权
US4267349A Process for the preparation of 2-substituted-alkyl-1-alkyl-nitroimidazoles 失效
2-取代 - 烷基-1-烷基 - 硝基咪唑的制备方法

Process for the preparation of
2-substituted-alkyl-1-alkyl-nitroimidazoles
摘要:
Novel 2-substituted 1-alkyl-nitroimidazoles and a process for their preparation by reaction of 2-methyl-nitroimidazoles with oxalic acid diesters, followed by reaction of the resulting nitroimidazol-2-yl-pyruvic acid esters with chlorine, in turn followed, if desired, by reaction of the resulting 2-dihalomethyl-nitroimidazoles with water.Both the novel and the known compounds obtainable by the process of the invention are valuable starting materials for the preparation of dyes, pesticides and drugs.
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