发明授权
- 专利标题： 8-Phenyl-purines and pharmaceutical compositions containing same
- 专利标题（中）： 8-苯基嘌呤和含有它们的药物组合物
-
申请号： US166709申请日： 1980-07-08
-
公开(公告)号： US4299834A公开(公告)日： 1981-11-10
- 发明人: Volkhard Austel , Eberhard Kutter , Joachim Heider , Willi Diederen
- 申请人： Volkhard Austel , Eberhard Kutter , Joachim Heider , Willi Diederen
- 申请人地址： DEX Ingelheim am Rhein
- 专利权人： Boehringer Ingelheim Gesellschaft mit beschrankter Haftung
- 当前专利权人： Boehringer Ingelheim Gesellschaft mit beschrankter Haftung
- 当前专利权人地址： DEX Ingelheim am Rhein
- 优先权： DEX2927988 19790711
- 主分类号： A61K31/52
- IPC分类号： A61K31/52 ; A61P9/04 ; C07D239/48 ; C07D473/00
摘要：
This invention is directed to 8-phenyl-purines of general formula ##STR1## wherein R.sub.1 is a hydrogen or halogen atom; an alkoxy group optionally substituted by alkylmercapto, alkylsulfinyl or alkylsulfonyl group; or an alkylmercapto, alkylsulfinyl or alkylsulfonyl group, whereby each alkyl moiety may contain from 1 to 3 carbon atoms, andR.sub.2 is an alkoxy group with from 1 to 3 carbon atoms, and their physiologically compatible acid addition salts. The compounds exhibit valuable pharmacological properties, particularly positive inotropic activity.