发明授权
US4345030A Microorganism mutant conversion of sterols to androsta-4-ene-3,17-dione
失效
固醇突变体转化为雄甾-4-烯-3,17-二酮的微生物突变体
- 专利标题: Microorganism mutant conversion of sterols to androsta-4-ene-3,17-dione
- 专利标题(中): 固醇突变体转化为雄甾-4-烯-3,17-二酮的微生物突变体
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申请号: US184722申请日: 1980-09-08
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公开(公告)号: US4345030A公开(公告)日: 1982-08-17
- 发明人: Merle G. Wovcha , Candice B. Biggs
- 申请人: Merle G. Wovcha , Candice B. Biggs
- 申请人地址: MI Kalamazoo
- 专利权人: The Upjohn Company
- 当前专利权人: The Upjohn Company
- 当前专利权人地址: MI Kalamazoo
- 主分类号: C07J1/00
- IPC分类号: C07J1/00 ; C12P33/00 ; C12P33/16
摘要:
Mutant which is used in a novel microbiological process to selectively degrade steroids having 17-alkyl side chains of from 2 to 10 carbon atoms, inclusive, to yield predominantly androst-4-ene-3,17-dione (AD) and small amounts of androsta-1,4-diene-3,17-dione (ADD). AD is a valuable intermediate to make useful steroids.
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