发明授权
- 专利标题: Immunogenic complex from N. gonorrhoeae
- 专利标题(中): 来自淋病奈瑟氏球菌的免疫原性复合物
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申请号: US294855申请日: 1981-08-20
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公开(公告)号: US4386066A公开(公告)日: 1983-05-31
- 发明人: Edward C. O'Rourke , W. Wardle Fullerton
- 申请人: Edward C. O'Rourke , W. Wardle Fullerton
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: A61K39/095
- IPC分类号: A61K39/095 ; C12N1/20 ; C12P21/00
摘要:
A vesicular, immunogenic, non-pyrogenic complex is obtained from isolates of N. gonorrhoeae by cultivating N. gonorrhoeae on a suitable nutrient medium; harvesting and centrifuging the cells; extracting the cell pellet with TRITON X-100 at alkaline pH; suspending the solids remaining after extraction in aqueous medium and precipitating in the cold with ethanol.
公开/授权文献
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