发明授权
US4414147A Methods of decreasing the hydrophobicity of fibroblast and other
interferons
失效
降低成纤维细胞和其他干扰素疏水性的方法
- 专利标题: Methods of decreasing the hydrophobicity of fibroblast and other interferons
- 专利标题(中): 降低成纤维细胞和其他干扰素疏水性的方法
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申请号: US255321申请日: 1981-04-17
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公开(公告)号: US4414147A公开(公告)日: 1983-11-08
- 发明人: Alexander M. Klibanov , Robert S. Langer
- 申请人: Alexander M. Klibanov , Robert S. Langer
- 申请人地址: MA Cambridge
- 专利权人: Massachusetts Institute of Technology
- 当前专利权人: Massachusetts Institute of Technology
- 当前专利权人地址: MA Cambridge
- 主分类号: A61K38/21
- IPC分类号: A61K38/21 ; A61K47/48 ; C07G7/00
摘要:
A method for improving the stability and usefulness of interferon, including human fibroblast interferon, is disclosed. In this method, interferon is bonded to a non-hydrophobic substance to create a molecular complex that is less hydrophobic than untreated interferon.
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