发明授权
- 专利标题: Ester derivatives of alkoxybenzoyldeoxyfluorouridine
- 专利标题(中): 烷氧基苯甲酰基脱氧氟尿苷的酯衍生物
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申请号: US291809申请日: 1981-08-10
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公开(公告)号: US4425335A公开(公告)日: 1984-01-10
- 发明人: Setsuro Fujii , Bompei Yasui , Mitsuo Nakamura , Mitsuru Hirohashi , Tomohisa Miyamoto , Kazuko Ando , Iwao Hashimoto , Naoki Umeda , Masahiro Kawasaki
- 申请人: Setsuro Fujii , Bompei Yasui , Mitsuo Nakamura , Mitsuru Hirohashi , Tomohisa Miyamoto , Kazuko Ando , Iwao Hashimoto , Naoki Umeda , Masahiro Kawasaki
- 申请人地址: JPX Osaka
- 专利权人: Funai Kakuhin Kogyo Kabushiki Kaisha
- 当前专利权人: Funai Kakuhin Kogyo Kabushiki Kaisha
- 当前专利权人地址: JPX Osaka
- 优先权: JPX55-126776 19800911
- 主分类号: C07H19/073
- IPC分类号: C07H19/073 ; A61K31/70 ; A61K31/7042 ; A61K31/7052 ; A61K31/7064 ; A61K31/7072 ; A61P35/00 ; C07H19/06 ; C07H19/08
摘要:
New ester derivatives of alkoxybenzoyldeoxyfluorouridine of the general formula ##STR1## wherein R stands for an alkoxy group having 1 to 4 carbon atoms, m for 1 or 2, and n for 3 or 4 with the proviso that when m is 2, the adjacent two R's may be combined to form an alkylenedioxy group as a whole. These derivatives are prepared by acylating a 2'-deoxy-3',5'-di-O-alkylcarbonyl-5-fluorouridine with corresponding benzoyl halides and are useful as active ingredients for anti-tumor agents, especially for oral administration.
公开/授权文献
- US5600525A ESD protection circuit for integrated circuit 公开/授权日:1997-02-04