发明授权
- 专利标题： 1-.sup.11 C-D-Glucose and related compounds
- 专利标题（中）： 1-11C-D-葡萄糖及相关化合物
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申请号： US342684申请日： 1982-01-26
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公开(公告)号： US4439414A公开(公告)日： 1984-03-27
- 发明人: Chyng-Yann Shiue , Alfred P. Wolf
- 申请人： Chyng-Yann Shiue , Alfred P. Wolf
- 申请人地址： DC Washington
- 专利权人： The United States of America as represented by the United States Department of Energy
- 当前专利权人： The United States of America as represented by the United States Department of Energy
- 当前专利权人地址： DC Washington
- 主分类号： A61K51/00
- IPC分类号： A61K51/00 ; A61K49/02
摘要：
The novel compounds 1-.sup.11 C-D-glucose, 1-.sup.11 C-D-mannose, 1-.sup.11 C-D-galactose, 2-.sup.11 C-D-glucose, 2-.sup.11 C-D-mannose and 2-.sup.11 C-D-galactose which can be used in nuclear medicine to monitor the metabolism of glucose and galactose can be rapidly prepared by reaction of the appropriate aldose substrate with an alkali metal .sup.11 C-labeled cyanide followed by reduction with a Raney alloy in formic acid.
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