A device for adjusting ink or moisture-application rolls to a feeding roll and a printing cylinder in a printing machine, which includes two eccentrics positioned on the shaft of the feeding roll and provided with radially extended rods pivotally connected to the piston rods of pneumatic working cylinders and two pivotable double-arm levers centrally positioned on the respective eccentrics and connected with their upper arms to the ink or moisture application rolls. Adjustment of the ink or moisture application rolls to the feeding roll is effected upon actuation of the working cylinder and rotation of the eccentrics and adjustment of the ink or moisture application rolls relative to the printing cylinder is effected upon the pivoting movement of the double-arm levers.