发明授权
US4485251A Process for the preparation of bis(perfluoroalkyl-alkylthio)alkanoic
acids and lactone intermediates thereof
失效
制备双(全氟烷基 - 烷硫基)链烷酸及其内酯中间体的方法
- 专利标题: Process for the preparation of bis(perfluoroalkyl-alkylthio)alkanoic acids and lactone intermediates thereof
- 专利标题(中): 制备双(全氟烷基 - 烷硫基)链烷酸及其内酯中间体的方法
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申请号: US452531申请日: 1982-12-23
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公开(公告)号: US4485251A公开(公告)日: 1984-11-27
- 发明人: Robert A. Falk
- 申请人: Robert A. Falk
- 申请人地址: NY Ardsley
- 专利权人: Ciba-Geigy Corporation
- 当前专利权人: Ciba-Geigy Corporation
- 当前专利权人地址: NY Ardsley
- 主分类号: C09K3/18
- IPC分类号: C09K3/18 ; C07C67/00 ; C07C313/00 ; C07C319/14 ; C07C323/52 ; C07C323/56 ; C07D307/32 ; C07D307/33 ; D21H17/09 ; D21H17/11
摘要:
Disclosed is a process for the preparation of a bis(perfluoroalkyl-alkylthio)alkanoic acid of the formula ##STR1## wherein each R.sub.f is independently perfluoroalkyl of 3 to 18 carbon atoms or perfluoroalkoxyperfluoroalkyl of 3 to 18 carbon atoms, or mixtures thereof;each A is independently alkylene of up to 6 carbon atoms or said alkylene interrupted by --O--; N(H)-- or --N(lower alkyl)--;R is hydrogen or alkyl of 1 to 6 carbon atoms;R.sub.1 is hydrogen or lower alkyl; andR.sub.2 is hydrogen, lower alkyl, aryl or aryl substituted lower alkyl;by reacting a perfluoroalkyl-alkyl mercaptan of the formulaR.sub.f --A--SH (II)with a lactone of the formula ##STR2## in the presence of a catalytic amount of a Lewis acid to form a perfluoroalkyl-alkylthio lactone of the formula ##STR3## and reacting said perfluoroalkyl-alkylthio lactone with additional perfluoroalkyl-alkylmercaptan of the formulaR.sub.f --A--SH (IIa)in the presence of a catalytic amount of a Lewis acid, to obtain said bis(perfluoroalkyl-alkylthio)alkanoic acid of formula (I).