发明授权
- 专利标题： 1-Substituted 1,4-dihydropyridines
- 专利标题（中）： 1-取代的1,4-二氢吡啶
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申请号： US490167申请日： 1983-04-29
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公开(公告)号： US4495192A公开(公告)日： 1985-01-22
- 发明人: Kenji Muto , Yoshinori Takemoto , Takao Hatta , Tamotsu Hashimoto , Koji Yamada , Minoru Watanabe
- 申请人： Kenji Muto , Yoshinori Takemoto , Takao Hatta , Tamotsu Hashimoto , Koji Yamada , Minoru Watanabe
- 申请人地址： JPX Tokyo
- 专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX57-71425 19820430
- 主分类号： A61K31/4427
- IPC分类号： A61K31/4427 ; A61K31/443 ; A61K31/4433 ; A61K31/455 ; A61P9/08 ; A61P9/10 ; A61P9/12 ; C07C67/00 ; C07C201/00 ; C07C205/56 ; C07D211/90 ; C07D211/94 ; C07D401/12 ; C07D405/12 ; C07D409/12
摘要：
A vasodilating or anti-hypertensive composition comprises a pharmaceutical carrier and an effective amount of a 1,4-dihydropyridine compound as an active ingredient. The 1,4-dihydropyridine compound may be represented by the following general formula: ##STR1## wherein R'.sub.1 and R'.sub.4 represent a hydrogen atom, R'.sub.2 and R'.sub.3 represent an alkyl group having 1-5 carbon atoms or a substituted heterocyclic group wherein a substituent is an N-benzylpiperidyl group, R'.sub.5 represents a nitro group, and R'.sub.6 and R'.sub.7 represent an alkyl group having 1-5 carbon atoms.
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